This drug is peddled on every street corner in America, and is found in every country in the world. It is psychoactive, a stimulant and addictive. Users say that it increases alertness and focus, and reduces fatigue. But the high does not last and addicts must keep consuming it in increasing quantities. Put this way, sipping coffee sounds more like an abomination than the world’s most accepted form of drug abuse. But centuries of familiarity have put people at their ease. In the coming years science is likely to create many novel drugs that boost memory, concentration and planning. These may well be less harmful than coffee-and will almost certainly be more useful. But will people treat them with as much tolerance? High time The new cognition-enhancing drugs are designed to treat debilitating diseases such as Alzheimer’s, attention-deficit disorder and schizophrenia. But because they act deep in neural pathways of the brain, some of them are bound also to enhance people’s power to think and learn (see article). Such drugs will inevitably be used by healthy people too. That is the lesson from medicines such as Ritalin (methylphenidate) and Provigil (modafinil), which are now widely used ‘off label’ […]