Scientists have turned skin cells from patients with Lou Gehrig’s disease into motor neurons that are genetically identical to the patients’ own neurons. An unlimited number of these neurons can now be created and studied in the laboratory, a capability which should result in a better understanding of the disease and, one day, lead to new treatments or even the production of healthy cells that can replace the diseased ones. ‘The hope of some scientists is that they might be able to harness stem cells and program them to generate pluripotent stem cell lines [capable of differentiating into many different types of cells] which have the genes of patients,’ said Kevin Eggan, co-author of a paper appearing July 31 in the online version of Science. ‘This would open up the possibility of producing a large supply of immune-matched cells to that patient that could be used in transplantation methodologies.’ ‘The other hope, and one that’s much closer upon us . . . is if you could produce the cell types that become sick in that person, you might be able to use them in the laboratory to come to understand basic aspects of the disease and take […]