Harvard Scientists Reverse the Ageing Process in Mice – Now for Humans

Stephan: 

Scientists claim to be a step closer to reversing the ageing process after rejuvenating worn out organs in elderly mice. The experimental treatment developed by researchers at the Dana-Farber Cancer Institute, Harvard Medical School, turned weak and feeble old mice into healthy animals by regenerating their aged bodies.

The surprise recovery of the animals has raised hopes among scientists that it may be possible to achieve a similar feat in humans – or at least to slow down the ageing process.

An anti-ageing therapy could have a dramatic impact on public health by reducing the burden of age-related health problems, such as dementia, stroke and heart disease, and prolonging the quality of life for an increasingly aged population.

‘What we saw in these animals was not a slowing down or stabilisation of the ageing process. We saw a dramatic reversal – and that was unexpected,’ said Ronald DePinho, who led the study, which was published in the journal Nature.

‘This could lead to strategies that enhance the regenerative potential of organs as individuals age and so increase their quality of life. Whether it serves to increase longevity is a question we are not yet in a position to answer.’

The ageing process is poorly understood, […]

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Rate of Eating Disorders in Kids Keeps Rising

Stephan:  Further evidence that our culture based on profit as the sole priority -- please do not interpret this to mean I am against profit -- not only is destroying the middle class financially, it is also degrading our physical health. Particularly our children who are becoming a generation of Fatty Lumpkins, with eating disorders. This is not what the Founders had in mind.

Eating disorders have risen steadily in children and teens over the last few decades, with some of the sharpest increases occurring in boys and minority youths, according to a new report.

In one startling statistic cited in the report, an analysis by the Agency for Healthcare Research and Quality found that hospitalizations for eating disorders jumped by 119 percent between 1999 and 2006 for kids younger than 12.

At the same time as severe cases of anorexia and bulimia have risen, so too have ‘partial-syndrome’ eating disorders — young people who have some, but not all, of the symptoms of an eating disorder. Athletes, including gymnasts and wrestlers, and performers, including dancers and models, may be particularly at risk, according to the report.

‘We are seeing a lot more eating disorders than we used to and we are seeing it in people we didn’t associate with eating disorders in the past — a lot of boys, little kids, people of color and those with lower socioeconomic backgrounds,’ said report author Dr. David Rosen, a professor of pediatrics, internal medicine and psychiatry at University of Michigan. ‘The stereotype [patient] is of an affluent white girl of a certain age. We wanted people to understand […]

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Inefficiency Hurts U.S. In Ranking of Health

Stephan:  This is further evidence that the Illness Profit model does not work. This is not about the dedication of the doctor's and nurses, or their lack of competence. It is profit as the only priority -- Illness Profit Healthcare -- that is wrong. This will be but the first of several such studies. Other researchers will want to replicate and take what this study shows and explore it further. I predict these conclusions will hold.

By any measure, the United States spends more on health care than any other nation. Yet according to the World Fact Book (published by the Central Intelligence Agency), it ranks 49th in life expectancy.

Why?

Researchers writing in the November issue of the journal Health Services say they know the answer. After citing statistical evidence showing that American patterns of obesity, smoking, traffic accidents and homicide are not the cause of lower life expectancy, they conclude that the problem is the health care system.

Peter A. Muennig and Sherry A. Gleid, researchers at the Mailman School of Public Health at Columbia University, compared the performance of the United States and 12 other industrialized nations: Australia, Austria, Belgium, Britain, Canada, France, Germany, Italy, Japan, the Netherlands, Sweden and Switzerland. In addition to health care expenditures in each country, they focused on two other important statistics: 15-year survival for people at 45 years and for those at 65 years.

The researchers say those numbers present an accurate picture of public health because they measure a country’s success in preventing and treating the most common causes of death – cardiovascular disease, stroke and diabetes – which are more likely to occur at these ages. Their data come […]

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Paying an Arm and a Leg

Stephan:  The costs of a hip replacement is a measurable point and, since the procedure is roughly the same, and the hip replacements in rough parity, wide cost differences can only mean a factor not connected to the medical procedure, as medicine. This data is very clear: the Illness Profit system is the source of this difference.

So many charts, so little blog. Which chart should I show you from yesterday’s release of the latest global comparison of healthcare prices? How about the cost of hip replacements? Here it is:

The ‘average’ number is a little hard to see, so here it is: $34,454. That’s 2x what it costs in Germany, 3x what it costs in France, and 6x what it costs in Switzerland. WTF?

This goes a long way toward explaining why hip replacements are so popular in the United States: they’re a huge profit center for doctors and hospitals. Keep this in mind the next time someone starts going on about how you never have to wait in line for a hip replacement in America. It’s not because our healthcare system is super efficient, it’s because doctors are super eager to perform them.

The full set of cost charts is here, and they’re pretty instructive. You can, if you want, try to make the case that we perform better hip replacements or do better angioplasties than other countries. But appendectomies? CT scans? Normal deliveries? As Aaron Carroll says about the astonishing numbers for routine CT scans and MRIs:

Why does it cost so much more […]

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Classified Papers Prove German Warnings to Bush

Stephan:  It wasn't just that Bush, Cheney, Feith, Rice, Wolfowitz and others were criminally culpable for starting a completely unnecessary war, in spite of all attempts to dissuade them. It was their utter amateurish incompetence. I have just finished reading imperial Life in the Emerald City a book I commend to your attention. If you react as I did it will leave you with jaw dropping astonishment at how utterly mediocre these people were as statesmen, and strategists. With each revelation it becomes clearer and more irrefutable that through their decisions they have stripped America of over a trillion dollars and killed hundreds of thousands, including thousands of Americans, and wounded and maimed hundreds of thousands more. History I think will be merciless, and accountability in this lifetime would be very appropriate. Thanks to James Spottiswoode.

A classified document obtained by SPIEGEL shows notes from a meeting between a top German diplomat and Condoleezza Rice just weeks before the Iraq invasion. It indicates steps by the German government to prevent the war and undermines claims in George W. Bush’s memoir that Gerhard Schröder indicated he would support the president should the US go to war.

Gerhard Schröder and Joschka Fischer made every effort they could. The German chancellor and foreign minister spared no effort with their appeals, whether in public or private, in small groups or with the eyes of the entire world upon them. In the end, though, it was all for naught. Then-United States President George W. Bush wouldn’t allow anyone to change his mind. He was dead set on launching a war against Iraqi dictator Saddam Hussein and thereby bringing ‘freedom,’ as he put it, to the Middle East. It was a freedom that Bush described as ‘ God’s gift to mankind.’

Over time, however, this would-be gift from God has grown to become the biggest foreign-policy disaster in US history since the Vietnam War. The
war in Iraq

and its subsequent occupation has cost more than 100,000 Iraqi civilians and over 4,000 American soldiers their […]

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