When the water receded after Hurricane Milo of 2030, there was a foot of sand covering the famous bow-tie floor in the lobby of the FontaineÂbleau hotel in Miami Beach. A dead manatee floated in the pool where Elvis had once swum. Most of the damage occurred not from the hurricane’s 175-mph winds, but from the 24-foot storm surge that overwhelmed the low-lying city. In South Beach, the old art-deco buildings were swept off their foundations. Mansions on Star Island were flooded up to their cut-glass doorknobs. A 17-mile stretch of Highway A1A that ran along the famous beaches up to Fort Lauderdale disappeared into the Atlantic. The storm knocked out the wastewater-treatment plant on Virginia Key, forcing the city to dump hundreds of millions of gallons of raw sewage into Biscayne Bay. Tampons and condoms littered the beaches, and the stench of human excrement stoked fears of cholera. More than 800 people died, many of them swept away by the surging waters that submerged much of Miami Beach and Fort Lauderdale; 13 people were killed in traffic accidents as they scrambled to escape the city after the news spread – falsely, it turned out – that one of the […]
Abstract
Glyphosate is an active ingredient of the most widely used herbicide and it is believed to be less toxic than other pesticides. However, several recent studies showed its potential adverse health effects to humans as it may be an endocrine disruptor. This study focuses on the effects of pure glyphosate on estrogen receptors (ERs) mediated transcriptional activity and their expressions. Glyphosate exerted proliferative effects only in human hormone-dependent breast cancer, T47D cells, but not in hormone-independent breast cancer, MDA-MB231 cells, at 10-12 to 10-6M in estrogen withdrawal condition. The proliferative concentrations of glyphosate that induced the activation of estrogen response element (ERE) transcription activity were 5-13 fold of control in T47D-KBluc cells and this activation was inhibited by an estrogen antagonist, ICI 182780, indicating that the estrogenic activity of glyphosate was mediated via ERs. Furthermore, glyphosate also altered both ERα and β expression. These results indicated that low and environmentally relevant concentrations of glyphosate possessed estrogenic activity. Glyphosate-based herbicides are widely used for soybean cultivation, and our results also found that there was an additive estrogenic effect between glyphosate and genistein, a phytoestrogen in soybeans. However, these additive effects of glyphosate contamination in soybeans need further animal study.
In or around 1978, America’s character changed. For almost half a century, the United States had been a relatively egalitarian, secure, middle-class democracy, with structures in place that supported the aspirations of ordinary people. You might call it the period of the Roosevelt Republic. Wars, strikes, racial tensions and youth rebellion all roiled national life, but a basic deal among Americans still held, in belief if not always in fact: work hard, follow the rules, educate your children, and you will be rewarded, not just with a decent life and the prospect of a better one for your kids, but with recognition from society, a place at the table.
This unwritten contract came with a series of riders and clauses that left large numbers of Americans – black people and other minorities, women, gay people – out, or only halfway in. But the country had the tools to correct its own flaws, and it used them: healthy democratic institutions such as Congress, courts, churches, schools, news organisations, business-labour partnerships. The civil rights movement of the 1960s was a nonviolent mass uprising led by black southerners, but it drew essential support from all of these institutions, which recognised the moral and legal […]
CHEYENNE, Wyo. (AP) - The U.S. Environmental Protection Agency has dropped plans to have outside experts review its theory that hydraulic fracturing may have played a role in groundwater pollution in Wyoming, and the agency no longer plans to write a final report on its research that led to the controversial finding a year and a half ago.
Instead, the EPA announced Thursday that state officials will lead further investigation into pollution in the Pavillion area in central Wyoming, including ways to make sure people there have clean drinking water.
‘We think this is the most pragmatic, quickest way to help the residents of Pavillion. We’re going to work hand in hand with the state to make sure this investigation moves forward,
Climate change is creating more frequent and more unpredictable extreme weather events, forcing insurers to change how they assess the risk of natural disasters hitting a specific area, the Geneva Association think tank said Monday.
‘Traditional approaches, which are solely based on analysing historical data, increasingly fail to estimate today’s hazard probabilities,
Remote Viewing the Year 2060
