In a case of science fiction meeting reality, microscopic “machines” have journeyed inside a living animal for the first time.
The tiny devices delivered a cargo of nano-particles into the stomach lining of a mouse.
The research by scientists at the University of California is published in the journal ACS Nano.
Medical applications for micro-machines include the release of drugs into specific locations within the body.
But until now, they have only been tested in laboratory cell samples.
A team led by Professors Liangfang Zhang and Joseph Wang from UC, San Diego fed the tiny motors to mice.
The machines, made of polymer tubes coated with zinc, are just 20 micrometres long – the width of a strand of human hair.
In stomach acid, the zinc reacts to produce bubbles of hydrogen, which propel the machines into the lining of the stomach, where they attach.
As the machines dissolve, they deliver their cargoes into the stomach tissue.
The researchers say the method may offer an efficient way to deliver drugs into the stomach, to treat […]