Two studies published this week in JAMA Internal Medicine add to an increasing body of research hinting at an association between cannabis legalization and a reduction in opiate use.

The researchers involved in both studies utilized records of opiate prescriptions reported by the Centers for Medicare and Medicaid services, and analyzed how the prescription trends changed as a result of state-level changes in marijuana policy. Both studies, which utilize a larger data set than previous studies designed to address the same question, broadly reached the same conclusion: there are fewer prescriptions for opiates filled after a state legalizes medical or recreational marijuana.

In one study, a researchers analyzed the total number of daily doses for any opioid medication prescribed in Medicare Part D — an optional prescription drug plan for Medicare recipients — in each state in each year. They found a significant reduction of opiate prescriptions in states that adopted some […]

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