The Real Story About Organoids: What You Should Know About “Brains In A Dish”

Stephan:  In neuroscience there are developments going on, almost unknown to people outside the field, that have the potential to change other species in ways that are almost inconceivable. If you grow a human brain in a mouse is it human? Here are some basics you should know.

We’ve heard a lot in the last few years about organoids, the so-called “brains in a dish” created in labs by neuroscientists. But as with many neuroscience topics, a wide gulf separates viral newsiness from reality. Scientists at Neuroscience 2019, the annual meeting of the Society for Neuroscience, gathered at a press panel to discuss the latest brain-organoid research, sift through ethical implications, and address where the science is going next.

First, what is a brain organoid?

Simply put, a brain organoid is tissue manufactured in a lab from human stem cells that mimics human brain tissue.

“In the last five years scientists figured out how to turn stem cells into 3D cell structures, and eventually [developed] so-called brain organoids, which look like not only cell types in the brain but also cell architectures,” according to session moderator Hongjun Song, PhD, professor at the University of Pennsylvania Perelman School of Medicine who studies neurogenesis and epigenetics.

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That is not, however, the same as saying they are human brains. Rather, organoids […]

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The flat-Earth conspiracy is spreading around the globe. Does it hide a darker core?

Stephan:  As this story illustrates there really is no level of willful ignorance to which large numbers of people will not sink if it serves some deeper need in their psyché.  Speaking to that, note the linkage between flat earthism and rightwing conspiracy beliefs. Willful ignorance has become one of the major trends defining American culture. If that were not so how could 41% of Americans still support a man who is a corrupt demonstrated criminal, liar, and molester of women for president?

Jeffrey Diaz, right, is selling flat earth maps at his booth during Flat Earth International Conference at Crowne Plaza Denver Airport. November 15, 2018. Hundreds of people who believe the Earth is flat attended the conference.
Credit: Hyoung Chang/The Denver Post/ Getty

“I don’t want to be a flat Earther,” David Weiss says, his voice weary as he reflects on his personal awakening. “Would you wake up in the morning and want everyone to think you’re an idiot?”

But Weiss is a flat Earther. Ever since he tried and failed to find proof of the Earth’s curve four years ago, he’s believed with an evident passion that our planet is both flat and stationary — and it’s turned his world upside down.
“I absolutely freaked out,” Weiss tells CNN in a phone interview. “It literally whips the rug out from underneath you.”
Now, Weiss finds it tedious to associate with the majority of people — though he “unfortunately” still has some friends who believe in a round […]

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Nearly All Mass Shooters Since 1966 Have Had 4 Things in Common

Stephan:  Finally, we are getting some solid data on mass shooters, and in several respects it is not what you might expect.

Mass shooting markers
Credit: Apu Gomes/Getty

The stereotype of a mass shooter is a white male with a history of mental illness or domestic violence. While that may be anecdotally true, the largest single study of mass shooters ever funded by the U.S. government has found that nearly all mass shooters have four specific things in common.

A new Department of Justice-funded study of all mass shootings — killings of four or more people in a public place — since 1966 found that the shooters typically have an experience with childhood trauma, a personal crisis or specific grievance, and a “script” or examples that validate their feelings or provide a roadmap. And then there’s the fourth thing: access to a firearm.

The root cause of mass shootings is an intensely partisan debate, with one side blaming mental health and the others blaming guns. Researchers hope that the findings in the study could usher in a more holistic and evidence-based […]

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Under Trump, LGBTQ Progress Is Being Reversed in Plain Sight

Stephan:  Almost every day I see some disgusting social policy or judgment from criminal Trump and his Congressional cult, always to a negative effect on some minority group. Sexually insecure men, like Trump and his cult seem to have a particularly hard time with the LGBTQ community, and do everything in their power to make their lives miserable. Here are the facts.

Credit: hellogiggles

When he campaigned for president, Donald Trump posed with the rainbow flag and became the first GOP nominee to mention LGBTQ citizens in his convention speech. In his first month as president, he signed an executive order stating he was “determined to protect the rights of all Americans, including the LGBTQ community.”

Yet since taking office, Trump’s administration has acted to dismantle federal protections and resources for LGBTQ Americans, particularly those gained under President Barack Obama.

In a reversal from the Obama administration, the Trump administration has repeatedly taken the position that laws and regulations that prohibit discrimination on the basis of sex do not cover a person discriminated against for being gay or transgender. The administration has also pushed for religious exemptions to civil rights laws, which experts say will make it easier to discriminate against LGBTQ individuals. The administration has taken particular aim at transgender people, barring them from joining the military.

The White House did not respond […]

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Scientists Have Carried Out the Biggest Ever study on Transgender Children — Here is What They Have Found

Stephan:  I find the hysteria over sexuality in the United States quite sad, and very harmful. Start with this, your eternal self, soul in religious terms, has no gender. The reincarnation research shows that one life may be as a male, another as a female. Discarnate personalities don't have penises or vaginas. Thus, I am glad to see some actual research, as opposed to the usual religious and moral nonsense, on the life and health, both mental and physical, of transgender children.

Credit: Getty

Trans children who live as the gender they identify with act and develop similarly to their cisgender counterparts, according to a new study.

In the largest ever study of transgender children, scientists recruited 317 3 to 12-year-old transgender children, 189 of their siblings, and 316 cisgender kids who acted as controls. The transgender participants had socially transitioned, meaning they were living as the gender they identify with rather than what they were assigned at birth. For instance, a child with a penis assigned a boy at birth who has come out as and is living as a girl.

To conduct the study, the researchers met families across North America, study co-author Selin Gülgöz, a postdoctoral researcher in the Department of Psychology at the University of Washington, told Newsweek. They spoke to children and parents about the former’s gender identity. That included showing kids toys and asking which ones they preferred, and quizzing them on how similar they felt to boys or girls. The cisgender control group followed the same steps.

“The most surprising finding is, […]

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