The Biden administration has 43 presidential nominees still awaiting confirmation in the Senate as Congress prepares to break for the holidays, a delay that is putting American national security and foreign policy interests in jeopardy around the world, the State Department said on Friday.

Any nominee not confirmed before the Senate ends its session, which is expected as soon as next week, will have to be renominated by the White House next year, leading to further delays. Those awaiting confirmation include Kurt M. Campbell, whom President Biden is trying to appoint as the deputy to Secretary of State Antony J. Blinken.

The blockade of diplomatic nominees has continued as many Republicans in Congress have sought to condition support for Mr. Biden’s foreign policy priorities on winning right-wing policy concessions. Some have shown a willingness to leave holes in the national security and diplomatic staff, even as the Biden administration confronts […]