It’s one of the most well-known tenets of modern medicine: An aspirin a day keeps the doctor away. But according to a trio of studies published Sunday in the New England Journal of Medicine, a daily low-dose aspirin regimen provides no significant health benefits for healthy older adults. Instead, it may cause them serious harm.
The primary study was a randomized, double-blind, placebo-controlled trial — considered the gold standard for clinical trials. Researchers at Monash University in Australia recruited nearly 20,000 people in that country and the United States, with a median age of 74. All of the participants were considered healthy at time of enrollment, with none known to suffer from heart disease, dementia or persistent physical disability.
Half of the study participants received 100 milligrams of aspirin a day; the other half received a placebo. (A typical “low dose” aspirin contains 81 milligrams of the drug).