A person with type 1 diabetes incurred annual insulin costs of $5,705, on average, in 2016. The average cost was roughly half that at $2,864 per patient in 2012, according to a report due to be released on Tuesday by the nonprofit Health Care Cost Institute (HCCI).

The figures represent the combined amount paid by a patient and their health plan for the medicine and do not reflect rebates paid at a later date.

The increasing cost of insulin has led some patients to put their own health at risk.

In recent months, anecdotal stories have cropped up from family members and patients describing the rationing of the life-saving medication because they could not afford out-of-pocket expenses for insulin. That has also led to some protests outside company headquarters of insulin makers.

HCCI said the jump in spending was driven primarily by higher insulin prices overall and, to a lesser extent, a shift toward more expensive insulin products. Average daily insulin use rose only 3 percent over the same five-year period, the report found.

“It’s not that individuals are using more insulin or that […]

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