Being overweight is linked to an increased risk for premature death, but which part of the body carries the added fat could make a big difference. Extra weight in some places may actually lower the risk.

Researchers, writing in BMJ, reviewed 72 prospective studies that included more than two and a half million participants with data on body fat and mortality. They found that central adiposity — a large waist — was consistently associated with a higher risk of all-cause mortality. In pooled data from 50 studies, each four-inch increase in waist size was associated with an 11 percent increased relative risk for premature death. The association was significant after adjusting for smoking, physical activity and alcohol consumption.

Waist size is an indicator of the amount of visceral fat, or fat stored in the abdomen around the internal organs. This kind of fat is associated with an increased risk for heart disease, Type 2 diabetes, cancer and Alzheimer’s disease.

But increased fat in two places appears to be associated with a lower risk of death. Three studies showed that each […]

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